At INSIGHT 2021, scientists and therapists, pharmaceutical industry and anthropology, philosophers, and chemists will come together to determine the potential place of LSD, psilocybin, DMT, MDMA, and other psychedelic substances in the treatment of mental disorders. In addition, we will discuss the use of non-pharmacological methods to alter and cultivate states of consciousness and all that it takes to build such unusual states of consciousness a legitimate and safe place in society.